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PHDegens, It’s Time for a DeSci Update.

Key Takeaways:

  • DeSci’s total market cap, excluding long-tail memecoins, is approximately $1.2 billion, accounting for just 0.035% of crypto’s total market cap.
  • While Ethereum still hosts 49% of projects launched during previous cycles, Solana is catching up, accounting for 40% of 2023 and 2024 projects.
  • Standout private rounds, such as BIO Protocol’s strategic round with Binance Labs, demonstrate a growing interest in the sector, particularly in biotech-focused projects.
  • AI is increasingly influencing DeSci, with projects like BeeARD utilizing multi-agent systems to tackle inefficiencies in hypothesis generation and IP deal flow.
  • Platforms like pump.science and Stadium Science are pioneering novel financial mechanisms to fund and accelerate research.

Introduction: The Rise of PHDegens

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Prior to joining Messari, Chris was the Growth Lead at a Paradigm and a16z-backed gaming startup called LootRush. His primary focus is Consumer Products, Music x Crypto, Gaming, Digital Art, and market buying local tops.

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Outline
  • Key Takeaways:
  • Introduction: The Rise of PHDegens
  • DeSci Sector Map
  • Sector Growth & Performance Metrics
  • Fundraising
  • Sectoral Trends and Narratives
  • Conclusion
Author
Prior to joining Messari, Chris was the Growth Lead at a Paradigm and a16z-backed gaming startup called LootRush. His primary focus is Consumer Products, Music x Crypto, Gaming, Digital Art, and market buying local tops.
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